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Consult your pharmacist or local overnatter clozaril waste disposal company for more details about how to safely discard your product. Clozaril Clozapine side effects Stop using clozapine and get emergency medical help if you have any of these signs of an allergic reaction: difficulty swelling of your face, lips, tongue, or throat. The absence of warning for given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Clozapine was introduced in the 1970s, but was banned for about decade because of rare but potentially deadly side effect: up to of patients lose their white blood cells while taking the drug. It is important to begin taking this drug at low dose, increasing your dose slowly, to lessen side effects such as dizziness, drowsiness and seizures. Patients should be advised of the risk of orthostatic hypotension, especially during the period of initial dose titration.